Levitra 20mg (vardenafil hydrochloride) is an FDA-approved oral phosphodiesterase type 5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED) in adult men. Vardenafil selectively inhibits PDE5, preventing the breakdown of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum during sexual stimulation. This leads to smooth muscle relaxation, increased arterial blood flow, and improved penile rigidity sufficient for satisfactory sexual performance.
The 20mg strength is the maximum recommended dose and is typically taken:
Clinical trials (including pivotal studies and real-world data) demonstrate that Levitra 20mg significantly improves:
Levitra is effective across a wide range of ED etiologies (vascular, neurogenic, psychogenic, mixed) and in men with comorbidities such as diabetes, hypertension, dyslipidemia, and post-prostatectomy ED. Onset of action is typically within 25–60 minutes (faster than sildenafil in some head-to-head studies), with duration up to 4–5 hours and a favorable window for spontaneity.
Common side effects are mild and transient: headache, flushing, nasal congestion, dyspepsia (indigestion), dizziness, and back pain—most often resolving quickly. Rare but serious risks include sudden vision loss (non-arteritic anterior ischemic optic neuropathy), sudden hearing loss, priapism (prolonged erection >4 hours requiring immediate medical attention), and cardiovascular events. Levitra is contraindicated with nitrates (risk of severe hypotension) and in patients with recent myocardial infarction, stroke, unstable angina, severe heart failure, or known hypersensitivity. Caution is advised in men with severe hepatic impairment, end-stage renal disease, retinitis pigmentosa, anatomical penis deformation (Peyronie’s), or those taking potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) or alpha-blockers (risk of hypotension).
Levitra 20mg requires a prescription and should be used only after a medical evaluation of cardiovascular risk, medication interactions, and underlying causes of ED (diabetes, hypertension, low testosterone, prostate issues, psychological factors). It is not indicated for women, children, or men without erectile dysfunction. For optimal results and safety, combine Levitra with healthy lifestyle practices—regular exercise, balanced diet, smoking cessation, limited alcohol, and stress reduction. Consult a healthcare provider to confirm if Levitra 20mg is appropriate for your needs, receive proper dosing instructions, and discuss any potential interactions or contraindications.
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