TB 500

Beschrijving

TB-500 (also known as Thymosin Beta-4 or its synthetic fragment) is an investigational synthetic peptide modeled after a naturally occurring protein found in nearly all human and animal cells, particularly studied in preclinical research for its regenerative and protective properties. It is believed to work by upregulating actin sequestration, promoting cell migration, angiogenesis (new blood vessel formation), anti-inflammatory effects, and tissue remodeling—mechanisms that may accelerate healing of tendons, ligaments, muscles, skin wounds, and even cardiac or neurological tissues in animal models. Preclinical studies (including those on wound healing, myocardial injury, and musculoskeletal repair) have shown promising results such as faster recovery from injuries, reduced scar formation, improved flexibility, decreased inflammation, and enhanced overall tissue regeneration, often with complementary benefits when combined with peptides like BPC-157 in anecdotal or wellness applications. In human contexts, TB-500 is commonly discussed in biohacking, athletic recovery, and regenerative medicine communities, with users typically administering it via subcutaneous or intramuscular injection (researched doses often in the range of 2-10mg per week, divided into smaller doses) or sometimes oral forms, reporting subjective improvements in injury recovery time, reduced pain, and better mobility. However, TB-500 is not FDA-approved for any human therapeutic use as of 2026—it remains classified as a research chemical or substance with significant safety concerns by regulatory bodies, including restrictions on compounding due to potential immunogenicity, unknown long-term effects, and risks like immune system disruption or promotion of abnormal cell growth in some animal data. It is banned by the World Anti-Doping Agency (WADA) for athletes due to its performance-enhancing potential and lack of approval. Human evidence is limited primarily to anecdotal reports, small observational data, and extrapolations from animal studies—no large-scale, randomized controlled trials confirm safety or efficacy in people. Reported side effects from user experiences are generally mild (fatigue, headaches, nausea, injection-site irritation, lightheadedness), but serious unknowns persist regarding long-term risks, purity in unregulated sources, potential interactions, or adverse effects like tumor acceleration in certain models. TB-500 should never be used without supervision from a qualified healthcare provider experienced in peptides, as self-administration carries risks of contamination, improper dosing, or unforeseen reactions. It is not a substitute for evidence-based medical treatments, physical therapy, or proven interventions for injury or inflammation. Always prioritize regulated therapies, consult a professional for personalized assessment, and avoid unapproved or black-market sources due to quality and legal concerns.