GHK-CU

Kuvaus

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex), also known as copper tripeptide-1, is a naturally occurring tripeptide found in human plasma, saliva, and urine that binds copper ions and exhibits powerful regenerative, protective, and anti-aging effects. Extensively researched since the 1970s (notably by Dr. Loren Pickart), GHK-Cu modulates multiple cellular pathways to stimulate collagen and elastin synthesis, promote glycosaminoglycan production, enhance wound healing, reduce inflammation, improve skin barrier function, and support tissue remodeling—often leading to firmer, smoother, more youthful-looking skin with reduced appearance of fine lines, wrinkles, and age-related thinning. Clinical and preclinical studies demonstrate its ability to accelerate dermal wound repair, increase skin density and elasticity, protect against UV damage, and even promote hair follicle growth and thicker, healthier hair when applied topically or researched in other contexts. In skincare formulations (serums, creams, and masks), GHK-Cu is widely used at concentrations around 0.1-2% for visible improvements in skin clarity, firmness, and overall vitality, with many users reporting noticeable results after consistent use over weeks to months. It is also explored in research for broader applications like anti-inflammatory effects in conditions such as colitis models, tissue regeneration, and potential longevity benefits through gene expression modulation. GHK-Cu is available in over-the-counter cosmetic products for topical use, which are generally considered safe and effective for skin and hair care. However, injectable forms (subcutaneous or intramuscular) remain investigational and are not FDA-approved for human therapeutic use—classified by the FDA as a bulk substance that may present significant safety risks (e.g., potential immunogenicity or impurities in compounding) for injectable routes, limiting legal availability to research or specific compounded prescriptions under medical supervision. Topical GHK-Cu products carry minimal side effects (occasional mild irritation or rare “copper peptide uglies” purging phase with temporary worsening of skin appearance), while any injectable use requires caution due to unknowns around long-term safety, dosing (often researched at 1-5mg daily), and interactions. GHK-Cu is not a miracle cure but a scientifically supported ingredient for skin rejuvenation, hair support, and healing when used appropriately. Always consult a healthcare provider or dermatologist before incorporating GHK-Cu (especially injectables) to ensure suitability for your needs, source from reputable suppliers, and combine with a holistic routine including sun protection, nutrition, and professional guidance for optimal results.

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