DeneB Classic S is a high-quality, monophasic, cross-linked hyaluronic acid (HA) dermal filler produced by BioPlus Co., Ltd. (South Korea), part of the DeneB series recognized for its advanced cross-linking technology, high purity, low BDDE residue, and uniform particle distribution. It contains 20 mg/mL of non-animal origin hyaluronic acid with a medium degree of cross-linking, delivering a smooth, elastic, and highly moldable gel that integrates seamlessly into tissue while providing moderate lifting capacity and natural movement.
DeneB Classic S is specifically formulated for mid-dermal injection to treat:
The product is supplied in a 1.1 mL pre-filled syringe with two 27G or 30G needles, allowing precise placement in mid-dermal layers. Results are visible immediately after injection, with optimal softness and integration apparent after swelling resolves (typically 5–14 days). Depending on injection depth, treatment area, patient metabolism, and lifestyle factors, effects usually last 9–12 months or longer in low-movement zones.
DeneB Classic S stands out due to:
Common side effects are mild and short-lived: injection-site swelling, bruising, redness, tenderness, or itching (generally resolving within 3–10 days). Rare complications can include prolonged swelling, asymmetry, nodules, vascular occlusion, or delayed hypersensitivity—proper injection technique, anatomical knowledge, aspiration before injection, and cannula use in high-risk areas are critical to minimize risks.
As of 2026, DeneB Classic S is CE-marked and widely used in Europe, Asia, the Middle East, Latin America, and other regions, but it is not FDA-approved in the United States (where similar medium-viscosity HA fillers include Juvederm Volift, Restylane Refyne, and Belotero Balance for moderate wrinkles and lip enhancement). It should only be administered by trained aesthetic physicians, dermatologists, or plastic surgeons experienced in hyaluronic acid fillers and facial anatomy.
Always combine DeneB Classic S treatments with a comprehensive pre-treatment consultation, medical history review, realistic expectation setting, and post-care instructions (avoid strenuous exercise, heat, alcohol, and certain supplements for 24–48 hours). For optimal longevity and safety, maintain stable weight, protect skin from UV exposure, and follow a good skincare routine. Consult a qualified injector for a personalized assessment and to determine if DeneB Classic S is the right choice for your wrinkle correction, lip enhancement, or mid-face contouring goals.